Sensitization to cat and dog components and prediction of symptoms in cat-sensitized children

Background Sensitization to cat and/or dog allergens during childhood represents a risk factor for the development of allergic diseases later in life. Objective The study investigated association patterns sensitization and allergen components with clinical symptoms allergy these furry animals among cat-sensitized children. Methods children were evaluated presence bronchial asthma, atopic dermatitis rhinitis. Their mothers completed questionnaire on pet exposure at home. Levels serum IgE epitopes Fel d (1, 2, 4), as well Can f 3, 5) measured all studied Results Respiratory following most common 2 epitope (p = 0.041). After contact dog, respiratory 1 0.042), both 0.009) 0.002), whereas eye occurred mostly 3 0.039). Conclusions Molecular diagnosis patients may help clinicians predict their severity.